Hsil CIN23 Management

14.05.2026 Prof. Dr. Cihan Kaya

HSIL / CIN 2-3 Management – Patient Information Guide

What is HSIL / CIN 2-3?

HSIL (High-grade Squamous Intraepithelial Lesion) and CIN 2-3 refer to moderate and severe cellular changes in the cervix. These lesions are considered precancerous and require careful management.

Important Information

HSIL / CIN 2-3 is not cancer, but if left untreated, there is a risk of progression to cancer over time.

General Approach

• Active treatment is usually necessary
• The goal is to completely remove the lesion

What Happens After Diagnosis?

• Definitive diagnosis is made with colposcopy and biopsy
• Differentiation between CIN 2 and CIN 3 is made

Treatment Options

• LEEP (LEETZ) – the most commonly preferred method
• Cold knife conization
• Rarely, ablation methods

What is LEEP (LEETZ)?

It is a procedure to remove abnormal tissue from the cervix using a thin wire loop. It provides both diagnosis and treatment.

CIN 2 Management

• In young patients (especially <25 years old): follow-up may be considered
• In other patients, treatment is generally recommended

CIN 3 Management

• Must be treated
• Follow-up is not sufficient

Post-Treatment Follow-up

• Smear and HPV test after 6–12 months
• Regular check-ups are very important

Pregnancy and HSIL

• Emergency treatment is generally not performed during pregnancy
• Postpartum evaluation is done

Clinical Fact

If HSIL / CIN 2-3 lesions are treated early, cervical cancer can largely be prevented.

Conclusion

HSIL / CIN 2-3 is a serious but treatable condition. Complete recovery can be achieved with appropriate treatment and follow-up.

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