Embryo Glue

What is Embryo Glue? – Comprehensive Guide

What is Embryo Glue?

Embryo glue is a special transfer solution containing hyaluronan (hyaluronic acid) used during embryo transfer. Its purpose is to facilitate the embryo's attachment to the inner lining of the uterus.

How Does It Work?

Hyaluronan is a molecule naturally found in the endometrium. It can support implantation by creating a biological bridge between the embryo and the uterus.

When Is It Used?

During embryo transfer, the embryo, taken into the transfer catheter, is placed into the uterus within a special solution.

Who Benefits Most?

• Recurrent IVF failure
• History of poor implantation
• Medium quality embryos
• Selected patient groups

Scientific Impact

Some studies have shown a slight increase in implantation and pregnancy rates. However, a significant benefit has not been proven in all patients.

Advantages

• Easy to apply
• Safe
• May provide additional implantation support

Disadvantages

• Incurs additional cost
• Its effect is not clear in every patient

Clinical Reality

Embryo glue alone does not determine success. Embryo quality and endometrial status are the most important factors.

Is It Safe?

Current data indicate that embryo glue use is safe, and no serious side effects have been reported.

Conclusion

Embryo glue is an auxiliary method that can be used to support implantation, especially in selected patients. However, routine use is not necessary for every patient.