Diaphragm Endometriosis

14.05.2026 Prof. Dr. Cihan Kaya

What is Diaphragmatic Endometriosis? – Comprehensive Guide

What is Diaphragmatic Endometriosis?

Diaphragmatic endometriosis is a rare but clinically significant condition caused by the implantation of endometrial tissue on the diaphragm. It is usually observed on the right hemidiaphragm.

Why Does It Occur?

It develops when endometrial tissue reaches the diaphragm via retrograde menstruation or lymphatic/hematological spread. It is often associated with advanced-stage endometriosis.

Symptoms

The most typical finding is right shoulder pain that increases during menstruation. Additionally, chest pain, shortness of breath, and rarely, catamenial pneumothorax may be observed.

Why Does Right Shoulder Pain Occur?

Diaphragmatic irritation causes pain referred to the shoulder via the phrenic nerve. For this reason, patients usually present with orthopedic or neurological complaints.

How Is It Diagnosed?

Diagnosis often begins with clinical suspicion. MRI and thoracic imaging can be helpful, but a definitive diagnosis is usually made by laparoscopy.

MRI Findings

Nodular or plaque-like lesions may be seen on the diaphragm. However, small lesions can be overlooked.

Surgical Treatment

Excision of lesions is performed using a laparoscopic or thoracoscopic approach. In advanced cases, a multidisciplinary approach is required.

Medical Treatment

Hormonal therapies (GnRH analogues, progesterones) can provide symptom control but do not completely eliminate the lesions.

Clinical Significance

Diaphragmatic endometriosis is often overlooked. It should always be kept in mind, especially in patients with menstruation-related shoulder pain.

Conclusion

Diaphragmatic endometriosis is a rare but important condition. It can be successfully managed with accurate diagnosis and an appropriate surgical approach.

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