When to Consider IVF?

14.05.2026 Prof. Dr. Cihan Kaya

When Should In Vitro Fertilization (IVF) Be Considered? – A Comprehensive Guide

What is In Vitro Fertilization (IVF)?

In vitro fertilization treatment is the process of fertilizing an egg and sperm in a laboratory setting and transferring the resulting embryo into the uterus.

When Should IVF Be Considered?

IVF treatment is preferred when pregnancy cannot be achieved naturally or in certain medical conditions.

1. Duration Based on Age

Under 35 years old: If pregnancy does not occur after 1 year of regular unprotected intercourse
Over 35 years old: If pregnancy does not occur within 6 months, IVF should be considered.

2. Fallopian Tube Problems

If the fallopian tubes are blocked or damaged, IVF is the most effective treatment method.

3. Male Factor

If sperm count, motility, or morphology is severely impaired, IVF/ICSI is preferred.

4. Endometriosis

In cases of advanced endometriosis, affected fallopian tubes, or long-standing inability to achieve pregnancy, IVF is recommended.

5. Low Ovarian Reserve

In patients with low AMH, high FSH, or a low antral follicle count, IVF can be planned without delay.

6. Unexplained Infertility

If all tests are normal but pregnancy does not occur, IVF may be an option.

7. Age Factor

For women aged 38 and older, it is recommended to consider IVF without delay.

8. Recurrent Miscarriages

In some cases, IVF can be planned with genetic testing (PGT).

9. Previously Unsuccessful Treatments

If treatments like intrauterine insemination (IUI) are unsuccessful, IVF is pursued.

10. Risk of Genetic Disease

In cases where genetic screening (PGT) of embryos is required, IVF is preferred.

Conclusion

The decision for IVF is individualized. The most appropriate time should be determined by evaluating age, ovarian reserve, medical conditions, and previous treatments together.

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