IVF Aspirin

14.05.2026 Prof. Dr. Cihan Kaya

Aspirin Use in IVF Treatment – A Comprehensive Guide

What is Aspirin?

Aspirin (acetylsalicylic acid) is a medication that has a blood-thinning effect at low doses. It can be used as a supportive treatment in some patients during the IVF process.

What is Aspirin Used for in IVF?

• To increase blood flow to the uterine lining (endometrium)
• To reduce microclot formation
• To support implantation

Who Uses It?

• Recurrent pregnancy loss
• Thrombophilia or clotting tendency
• Antiphospholipid syndrome
• Selected recurrent IVF failure

Is Routine Use Necessary?

No. Routine aspirin use is not recommended for all patients. It is only beneficial in specific patient groups.

When is it Started?

It is usually started during the egg development process or before embryo transfer. It varies according to doctor's recommendation.

Method of Use

It is used in the form of low-dose aspirin (usually 75–100 mg/day).

Side Effects

• Stomach sensitivity
• Reflux
• Increased bleeding tendency

Who Should Use it Cautiously?

• Those with stomach ulcers
• Those with bleeding disorders
• Those with a history of allergies

Use with Blood-Thinning Injections

In some patients, a combination of aspirin + heparin may be used. This is entirely an individual decision.

Clinical Fact

Aspirin may be beneficial in the right patient, but it is not certain that it increases pregnancy rates in every patient.

Conclusion

Aspirin is a supportive treatment used in selected patients during IVF treatment. It must be used under doctor's recommendation.

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