Increasing IVF Success

To Increase IVF Success (IVF) – Clinical and Practical Guide

General Approach

IVF success is not dependent on a single factor. Embryo quality, endometrium, patient age, and treatment strategy are collectively determinant.

1. Correct Patient and Protocol Selection

• Stimulation based on AMH and AFC
• Antagonist vs specific protocol selection
• Personalized treatment approach

2. Egg and Sperm Quality

• Smoking and alcohol should be quit
• Antioxidant supplements can be used
• Advanced sperm selection techniques if male factor exists

3. Embryo Quality

• Blastocyst culture
• PGT in necessary patients
• Time-lapse and AI-assisted selection

4. Endometrial (Uterus) Preparation

• Thickness ≥7-8 mm
• Trilaminar structure
• Hysteroscopy if necessary

5. Transfer Strategy

• Fresh vs frozen transfer selection
• Freeze-all approach (in high-risk cases)
• Single embryo transfer (based on quality)

6. Lifestyle

• Balanced nutrition
• Regular sleep
• Stress control
• Light exercise

7. Medical Supports

• Progesterone support
• Aspirin / heparin in selected patients
• Steroid in necessary patients

8. OHSS and Complication Prevention

• Appropriate dose stimulation
• GnRH agonist trigger
• Close monitoring

9. Post-Transfer Process

• Adherence to medication
• Avoiding excessive activity
• Reducing unnecessary stress

10. Clinical Experience

An experienced center and embryology laboratory play an important role in IVF success.

Clinical Reality

The most important determinant factors are: the genetic health of the embryo and female age.

Conclusion

A holistic and personalized approach is required to increase IVF success. There is no single miracle method; the right combination brings success.